An experimental study of domestic bone cement used on percutaneous vertebroplasty
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 10
- DOI:
- 10.3760/j.issn:1005-1201.2004.10.001
- Key Word:
- 聚甲基丙烯酸类;放射学,介入性;生物力学实验;脊柱骨折
Abstract： 目的评估不同配制比例的国产及进口骨水泥的材料性能,及椎体成形术后其对尸体脊柱压缩性骨折标本生物力学性能的影响.方法将改变配制比例的国产骨水泥[粉液比(g/ml)为3∶ 2;粉剂中BaSO4的含量为20%]及进口骨水泥(配比方案采用厂家推荐比例)分成2组,每组各8个样本,测定其聚合时间、强度及刚度.搜集4具老年女性尸体的20个腰椎,将标本置于材料实验机上制成压缩性骨折的模型,并测定椎体的刚度及强度.然后按随机数字表法随机分成2组,一组用国产骨水泥,另一组使用进口骨水泥对尸体标本行椎体成形术,术后于CT机上行轴面扫描,然后再次测量其刚度和强度.结果改变配制比例后国产骨水泥的材料刚度为(2711.8±612.3)N/mm,而进口骨水泥为(2874.7±457.6) N/mm,两者间差异无显著性意义(t= 0.609,P＞0.05).但国产骨水泥的材料强度为(7271.3±365.4)N,低于进口骨水泥(8481.3±397.3)N,两者间差异存在显著性意义(t=6.281,P＜0.05).两组骨水泥皆能使椎体的刚度及强度较骨折前得到加强,其中国产组使椎体的强度恢复至(1.226±0.44)MPa,而进口组恢复至(1.202±0.38) MPa,两者之间差异无显著性意义(F=0.001,P＞0.05);国产组使椎体的刚度恢复至(571.4±184.2)N/mm,而进口组恢复至(518.7±164.7)N/mm,两者相比差异无显著性意义(F=2.297,P＞0.05).国产及进口组骨水泥在椎体内的CT值分别为(2982.9±102.0)HU及(1554.3±172.7)HU,两者间差异有显著性意义(t=22.525,P＜0.05).结论经国产或进口骨水泥加固的骨折椎体皆能获得满意的生物力学性能,国产骨水泥在椎体内的X线显影效果良好,但上述结果还需进一步的临床研究证实.
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