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CT-guided percutaneous permanent 125I implantation for patients with malignant tumor
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 9
- DOI:
- 10.3760/j.issn:1005-1201.2004.09.006
- Key Word:
- 肿瘤,各部位;碘放射性同位素;放射学,介入性;近距离放射疗法
Abstract： 目的评价CT导引下瘤体内125I粒子植入治疗恶性肿瘤的可行性、安全性及其疗效.方法 10例13个病灶行CT导引下瘤体内125I粒子植入,其中原发肿瘤4例,转移瘤6例(9个病灶).患者男 4例,女6例,年龄54～62岁(平均56.9岁) .依据粒子植入术前15 d内CT图像应用计算机治疗计划系统制定粒子植入计划,按治疗计划在CT导引下穿刺植入125I粒子.植入术后立即CT扫描及术后5～10个月CT扫描观察粒子在瘤体内的分布、有无并发症发生及疗效.结果 10例粒子植入均顺利完成,粒子分布满意,单个瘤体内植入125I粒子数为1～44粒(平均18.6粒).未见急性并发症和治疗相关的放射损伤.全部4例疼痛患者粒子植入术后疼痛均有明显减轻.随诊CT检查示3个病灶消失, 8个病灶明显缩小, 其余2个病灶大小无明显变化.植入术前及植入术后随诊显示病灶平均大小分别为3.15和2.06 cm(t=5.127, P<0.001).结论 CT导引下125I粒子植入近距离放射治疗对原发及转移性恶性肿瘤是1种安全、可行、有效的治疗方法.
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