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Comparison study of human brain response to acupuncture stimulation vs finger tapping task by using real time fMRI

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF RADIOLOGY

Issue:: 3

DOI:: 10.3760/j.issn:1005-1201.2002.03.005

Key Word:: 针刺;磁共振成像;脑

Abstract：目的利用血氧水平依赖(blood oxygen level depended ,BOLD) 实时动态功能磁共振成像技术观察针刺人体足三里和阳陵泉穴对脑运动功能区的影响,并对针刺机理进行初步探讨.方法 17例健康志愿者,行实时动态功能磁共振成像.每人分别接受以下2项任务:(1)右手对指运动;(2)被针刺右侧足三里和阳陵泉.检测感兴趣区的相关系数,感兴趣区包括两侧的躯体感觉运动区(SMC)、运动前区(PMC)和副运动区(SMA).对被激活的感兴趣区进行计数.采用SAS软件包作精确概率法检验对两组资料进行分析.结果对指任务除去1例合作不好,其余16例激活右侧(SMCR) 8例,PMCR 8例,SMA 9例,左侧(SMCL) 16例,PMCL 9例.针刺任务3例运动伪影明显没有获得满意图像,另有2例脑功能区无明显激活,其余12例次激活SMCR 6例,PMCR 10例,SMA 8例,SMCL 11例,PMCL 10例.精确概率法检验Fisher′s exact test (2-Tail) P>0.05,说明2种刺激兴奋感兴趣区的差异无显著性意义.结论脑功能磁共振成像在针刺机制和应用价值研究领域具有重要作用;但其实用价值尚需结合临床针刺效果进行综合评价和进一步探讨.

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