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Functional MRI studies of acupuncture analgesia modulating within the human brain
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1005-1201.2002.03.004
- Key Word:
- 针刺镇痛;磁共振成像;脑
Abstract： 目的用功能磁共振成像(functional magnetic resonance imaging,fMRI)方法研究与针刺镇痛有关的脑功能区. 方法针刺8例健康右利手志愿者的右侧大肠经合谷穴,同时进行全脑的fMRI扫描,用t检验分析获得针刺刺激状态与静息状态信号对比的脑功能图像. 结果 8例受试者中6例的资料符合研究条件而被采用.针刺引起的信号升高与信号降低出现于不同的多个脑区(t≥2 345, P<0 01),其中中脑导水管周围灰质和左侧豆状核区的信号升高,以及双侧前扣带回区和双侧枕叶的信号降低,被认为可能是与针刺镇痛有关的脑区反应. 结论用fMRI方法研究表明,针刺镇痛效果可能是通过多个脑功能区的相互作用而产生的.
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