You Position: Home > Paper
Mapping cortical areas associated with Chinese word processing with functional magnetic resonance imaging
( views:220, downloads:80 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1005-1201.2002.03.002
- Key Word:
- 语言试验;语义区别;磁共振成像;半球优势,大脑
Abstract： 目的使用功能磁共振成像(fMRI)对参与汉字处理的脑皮层区域进行确认,并对fMRI在人脑功能区定位方面的可靠性及重复性进行探讨.方法对8例右利手、母语为汉语的正常年轻人进行了汉语同义字和同音字判断的测试,同时采集其脑部的fMRI数据.MRI检查分别在2台不同的机型上完成(1.5 T GE Signa Horizon和1.5 T Siemens Vision).通过相关分析进行统计学处理并得到脑功能活动的图像.结果对同义字和同音字进行判断均能明显激活Broca区、Wernicke区、双侧纹外视区及双侧颞叶腹侧皮层.配对t检验显示执行同义字和同音字判断任务所激发的脑功能区之间无显著性差异(t=0.35,P>0.05), 在2台不同机型的MRI仪上获得的结果无本质区别.结论 fMRI可以对汉语处理的有关大脑皮层区域进行定位,在不同临床MRI机型上得到的结果不仅可靠,而且具有很好的重复性.
- [1]李少武,戴建平,朱明旺,等.累及大脑皮层运动区的颅内病变手术前后磁共振功能成像[J].2001,(2).
- [2]张淑倩,刘连祥,吴杰,等.人脑视皮质功能MRI的初步研究及临床应用[J].2001,(7).
- [3]李恩中,翁旭初,韩璎.语言与音乐刺激下脑功能活动的MR功能成像研究[J].1999,(5).
- [4]Takeshi Hatta.Recognition of Japanese kanji in the left and right visual fields[J].1977,15(4-5).
- [5]R W, Cox.AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.[J].1996,29.
- [6]Wada Juhn,Rasmussen Theodore.Intracarotid Injection of Sodium Amytal for the Lateralization of Cerebral Speech Dominance[J].1960.
- [7]Ding YS,Weng X,Volkow ND.Imaging the functioning human brain.[J].1999,96(20).
- [8]Binder JR,Swanson SJ,Hammeke TA,etc.Determination of language dominance using functional MRI: a comparison with the Wada test.[J].1996,46(4).
- [9]C. J. Price,R. J. S. Wise,R. S. J. Frackowiak.Demonstrating the Implicit Processing of Visually Presented Words and Pseudowords[J].1996,6(1).
- [10]Chee MW,Thiel T,Tan EW.Mandarin and English single word processing studied with functional magnetic resonance imaging.[J].1999,19(8).
- [11]C, Tegeler,S C, Strother,J R, Anderson,etc.Reproducibility of BOLD-based functional MRI obtained at 4 T.[J].1999,7(4).
- [12]S E, Petersen,P T, Fox,M I, Posner,etc.Positron emission tomographic studies of the cortical anatomy of single-word processing.[J].1988,331.
- [13]O J, Tzeng,D L, Hung,B, Cotton.Visual interalisation effect in reading Chinese characters.[J].1979,282(5738).
- [14]Petersen SE,Fiez JA.Neuroimaging studies of word reading.[J].1998,95(3).
- [15]J. E.Desmond,J. M.Sum,A. D.Wagner,etc.Functional MRI measurement of language Lateralization in Wada-tested patients[J].1995,118(6).
- [16]M E, Raichle,J A, Fiez,T O, Videen,etc.Practice-related changes in human brain functional anatomy during nonmotor learning.[J].1900,4.
- [17]S E, Petersen,J A, Fiez.The processing of single words studied with positron emission tomography.[J].1993,16.