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Etiology of primary ovarian insufficiency and premature ovarian failure
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 12
- DOI:
- 10.3321/j.issn:0529-567X.2008.12.005
- Key Word:
- No keyword available
Abstract： @@ 目前,卵巢早衰(premature ovarian failure,POF)是被广泛接受和应用的专业术语,通常是指女性40岁之前闭经,伴有高卵泡刺激素(FSH)和低雌激素水平.由于临床治疗很棘手,如何预防和预测POF的发生风险,成为临床医生关注的焦点.尽管在POF发病机制的探讨中,染色体结构或数目异常、自身免疫功能、医源性及环境等相关因素与POF发病的相关性研究已取得很大进展,但仍有部分POF患者的病因不清,称为"特发性POF".
- [1]Balasch J,Cervera R.Bidirectional effects on autoimmunity and reproduction.[J].2008,14(4).
- [2]De-Baere E,Veitia RA,Nallathambi J,etc.A novel polyalanine expansion in FOXL2: the first evidence for a recessive form of the blepharophimosis syndrome (BPES) associated with ovarian dysfunction.[J].2007,121(1).
- [3]Qin YY,Choi Y,Zhao H,etc.NOBOX homeobox mutation causes premature ovarian failure[J].2007,81(3).
- [4]Chen ZJ,Kovanci E,Zhao H,etc.Analysis of LHX8 mutation in premature ovarian failure.[J].2008,89(4).
- [5]Kalu E,Panay N.Spontaneous premature ovarian failure: management challenges.[J].2008,24(5).
- [6]Joe Leigh Simpson.Genetic and Phenotypic Heterogeneity in Ovarian Failure: Overview of Selected Candidate Genes[J].2008,1135(0).
- [7]Barra GB,Lofrano-Porto A,Casulari LA,etc.Luteinizing hormone beta mutation and hypogonadism in men and women.[J].2007,357(9).
- [8]Robinson WP,Hanna CW,Bretherick KL,etc.Estrogen receptor alpha gene polymorphisms are associated with idiopathic premature ovarian failure.[J].2008,89(2).
- [9]Welt CK.Primary ovarian insufficiency: a more accurate term for premature ovarian failure.[J].2008,68(4).
- [10]Zhao H,Chen ZJ,Qin Y,etc.Transcription factor FIGLA is mutated in patients with premature ovarian failure.[J].2008,82(6).
- [11]Chiauzzi VA,Charreau EH,Dain L,etc.Screening of FSH receptor gene in Argentine women with premature ovarian failure (POF).[J].2004,222(1).
- [12]Angrilli F,Falorio S,Fioritoni G.Gonadotropin-releasing hormone analog treatment for the prevention of treatment-related ovarian failure and infertility in women of reproductive age with Hodgkin lymphoma.[J].2008,49(6).