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Studies on mother-to-infant transmission of hepatitis C virus (HCV) and hepatitis G virus (HGV) co-infection
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 7
- DOI:
- 10.3760/j.issn:0529-567X.2004.07.003
- Key Word:
- 肝炎,丙型;GB病毒G型;黄病毒科感染;肝炎,病毒性,人;疾病传播,垂直
Abstract： 目的探索丙型肝炎病毒(HCV)、庚型肝炎病毒(HGV)混合感染的母婴传播情况及其影响因素.方法应用第3代酶联免疫吸附(ELISA)法,检测4506例孕妇血清HCV抗体(抗HCV),其中878例检测HGV抗体(抗HGV),用荧光定量PCR( FQ-PCR)方法,检测孕妇血清HCV RNA 、HGV RNA.结果 HCV RNA 和HGV RNA均阳性孕妇10例,其所分娩的11例新生儿中,HCV RNA阳性2例、HGV RNA阳性2 例;阴道分娩3例、急诊剖宫产分娩1例.母乳喂养4例,孕妇临产前丙氨酸转氨酶(ALT)升高3例.结论孕妇HCV和HGV混合感染并不增加母婴传播率.阴道分娩、孕妇临产前ALT升高及母乳喂养是HCV、HGV混合感染母婴传播的高危因素.
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