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Investigation on the gene expression pattern in cervical squamous cell carcinoma of uygur
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 6
- DOI:
- 10.3760/j.issn:0529-567X.2003.06.003
- Key Word:
- 宫颈肿瘤;癌,鳞状细胞;维吾尔族;寡核苷酸序列分析;基因表达谱;基因表达调控,肿瘤
Abstract： 目的探讨新疆维吾尔族妇女子宫颈鳞癌相关基因群的表达和功能.方法应用含有2 048条人类全长基因的cDNA表达谱基因芯片,对3例临床切除的宫颈癌及自身正常宫颈组织标本的基因表达谱进行分析.结果在3例宫颈鳞癌组织中有共同差异表达的基因64条,其中表达量减少(下调)的基因11条,表达量增加(上调)的基因53条.结论应用基因芯片技术可以快速、高通量的筛查出维吾尔族妇女宫颈鳞癌的相关基因.
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