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Comparison study on transvaginal ultrasonographic measurement and cytokine in prediction of the cervical ripening and the onset time of term labor
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 12
- DOI:
- 10.3760/j.issn:0529-567X.2002.12.002
- Key Word:
- 宫颈成熟;超声检查;细胞活素类
Abstract： 目的探讨阴道超声、细胞因子--白细胞介素(IL)6、8及人绒毛膜促性腺激素(hCG)对足月妊娠宫颈成熟度、临产时间的预测价值.方法检测79例足月初产妇宫颈阴道分泌液IL-6、IL-8及hCG水平;通过阴道超声测量孕妇宫颈长度、宫颈内口楔形区宽度、前羊膜囊长度;同时进行宫颈Bishop评分.结果 (1)IL-6、IL-8、hCG临产后水平[分别为(782±508)ng/L、(10 539±8 680) ng/L、(114±86) IU/L]较临产前[分别为(155±75)ng/L、(7 113±6 050) ng/L、(35±21) IU/L]显著升高,差异有极显著性(P<0.05).(2)IL-6、IL-8、hCG、宫颈长度、前羊膜囊长度均与宫颈Bishop评分显著相关(r=0.42、0.24、0.44、-0.56、0.35,P<0.05).(3)IL-6、IL-8、宫颈长度、前羊膜囊长度、宫颈Bishop评分均与临产时间显著相关(r=-0.42、-0.46、0.64、-0.52、-0.41,P<0.01);且均能预测1周内临产,其中宫颈长度的预测效果最好.宫颈长度≤30 mm者,预测其在1周内分娩的灵敏度、特异度、阳性预测值、阴性预测值分别为0.83、0.89、0.91、0.81.(4)多因素分析显示:阴道超声测量宫颈长度,预测宫颈成熟度和临产时间的价值优于其他指标.结论孕妇宫颈阴道分泌液IL-6、IL-8、宫颈Bishop评分及阴道超声测量宫颈长度、前羊膜囊长度,均能预测足月妊娠宫颈成熟度和临产时间,其中宫颈长度的预测价值最高.
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