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Prevention and trcatment of recurrent urinary system infection with estrogen cream in postmenopausal women
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 9
- DOI:
- 10.3760/j.issn:0529-567X.2001.09.005
- Key Word:
- 绝经后期;泌尿道感染;雌激素类
Abstract： 目的探讨阴道使用雌激素治疗绝经后妇女反复泌尿系感染的效果及可行性.方法将45例有反复泌尿系感染病史的绝经后妇女分成两组,分别使用结合雌激素(商品名倍美力),软膏30例(结合雌激素组),口服抗生素15例(抗生素组),疗程3个月.用药前、后分别行清洁中段尿尿常规检查、尿及阴道细菌培养,对阴道细胞成熟值及阴道健康情况进行评估.同时测定子宫内膜厚度及血清雌二醇水平.结果除结合雌激素组有3例自行停止治疗外,其余均完成治疗.治疗后结合雌激素组泌尿系感染的发生率(2/27)明显低于抗生素组(12/15),两组比较,差异有极显著性(P＜0.001).结合雌激素组阴道乳酸杆菌检出率达59.3%,抗生素组无乳酸杆菌出现.结合雌激素组阴道健隶评分(13.4±2 5)分;阴道细胞成熟值(74.6±14.1),分别明显高于抗生素组(5.2±0.4分;10.8±8.3),两项组问比较,差异均有显著性(P＜0.05).结论阴道局部使用雌激素,能有效减少绝经后妇女泌尿系感染的反复发作,较使用抗生素副反应轻,治疗效果明显提高.
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