Parametric imaging for characterizing clear cell renal cell carcinoma with contrast-enhanced ultrasound
- Author:
- No author available
- Journal Title:
- Chinese Journal of Ultrasonography
- Issue:
- 10
- DOI:
- 10.3760/cma.j.issn.1004-4477.2012.10.013
- Key Word:
- 超声检查;微气泡;肾肿瘤;腺癌,透明细胞;Ultrasonography;Microbubbles;Kidney neoplasms;Adenocarcinoma,clear cell
Abstract： Objective To investigate the features of quantitative analysis and parametric imaging of contrast-enhanced ultrasound (CEUS) in renal clear cell carcinoma (ccRCC).Methods Ninety-seven pathologically confirmed ccRCCs underwent conventional ultrasound and CEUS.Both quantitative parameters and dynamic vascular pattern (DVP) reconstructure were analyzed with Sonoliver software.Four types of DVP curves were described with type Ⅰ (Unipolar +),type Ⅱ (Bipolar + /-),type Ⅲ (Bipolar -/+) and type Ⅳ (Unipolar-),while the DVP parametric images,similarly,were divided into four types,with type Ⅰ,Ⅱ,Ⅲ and Ⅳ,respectively.Results As for the parameter of CEUS,there were statistical differences in maximum intensity (IMAX),area under the curve (AUC) and mean transit time (mTT) (P ＜0.05) and no statistic differences in rise time (RT) and time to peak (TTP) between ccRccs and peripheral renal parenchyma.Concerning of DVP of ccRCCs,type Ⅰ,Ⅱ,Ⅲ and Ⅳ accounted for 58.8％ (57/97),11.3％ (11/97),10.3％ (10/97) and 19.6％ (19/97) respectively.As for each type in DVP parametric images,the percentages were 58.8％ (57/97),11.3％ (11/97),8.2％ (8/97),21.7％ (21/97),respectively.Conclusions Quantitative analysis and parametric imaging can depict different features of vascularity in ccRCCs and improve the diagnosis of the tumors.
- [1]李萍,李凤华,方华,等.肾脏良恶性病灶微循环血流灌注定量分析中超声造影伽马拟合分析技术的应用[J].2009,(6).
- [2]黄备建,王文平,丁红,等.小肾癌的超声造影表现[J].2009,(5).
- [3]林满霞,徐辉雄,谢晓燕,等.肝细胞性肝癌超声造影参数成像临床应用研究[J].2010,(5).
- [4]Xie XY,Lu MD,Xu HX,etc.Renal cell carcinoma: real-time contrast-enhanced ultrasound findings.[J].2010,35(6).
- [5]Mercier, L.,Anaye, A.,Meuwly, J.-Y.,etc.Parametric imaging for characterizing focal liver lesions in contrast-enhanced ultrasound[J].2010,57(11).
- [6]Xu ZF,Xu HX,Xie XY,etc.Renal cell carcinoma and renal angiomyolipoma: differential diagnosis with real-time contrast-enhanced ultrasonography.[J].2010,29(5).
- [7]Chen Y,Zhou,Jiang J.Clear cell renal cell carcinoma: contrast-enhanced ultrasound features relation to tumor size.[J].2010,73(1).
- [8]Paul,Cairns.Renal cell carcinoma.[J].2010,9.
- [9]Marianne Gauthier,Ingrid Leguerney,Jessie Thalmensi,etc.Estimation of intra-operator variability in perfusion parameter measurements using DCE-US[J].2011,(3).
- [10]Lassau N,Chebil M,Chami L,etc.Dynamic contrast-enhanced ultrasonography (DCE-US): a new tool for the early evaluation of antiangiogenic treatment.[J].2010,5(1).
- [11]Meuli R,Frinking P,Peetrons P,etc.Differentiation of focal liver lesions: usefulness of parametric imaging with contrast-enhanced US.[J].2011,261(1).
- [12]Yan,Guo,Qian,etc.Differentiation of CT scan diagnosis between minimal fat renal angiomyolipoma with sufficient blood supply and clear cell renal carcinoma[J].2011,(1).