Which is the best peri-operative anti-coagulative therapy of transverse sinus stenting for refractory idiopathic intracranial hypertension?

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Author:
MEI Qi-yong(Department of Neurosurgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China)
XIAO Wen-ze(Worldwide Medical Center, Huashan Hospital, Shanghai Medical Colledge, Fudan University, Shanghai 200040, China)
CHEN Huai-rui(Department of Neurosurgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China)
BAI Ru-lin(Department of Neurosurgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China)
SUN Ke-hua(Department of Neurosurgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China)
HOU Li-jun(Department of Neurosurgery, Shanghai Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China)
Journal Title:
Chinese Medical Journal
Issue:
Volume 125, Issue 16, 2012
DOI:
10.3760/cma.j.issn.0366-6999.2012.16.029
Key Word:
pseudotumor cerebri;therapy;angiography;stents

Abstract: Treatment of refractory idiopathic intracranial hypertension (ⅡH) is a challenging problem.We reported a refractory ⅡH patient who manifested with typical intracranial hypertensive symptoms successfully treated with endovascular stent implantation.Pre-operative cerebrospinal fluid (CSF) opening pressure is 36 cmH2O.Cerebral angiography demonstrated a stenotic lesion located at the right transverse sinus (TS).The stenotic TS returned to its normal caliber and the pressure gradient deceased from 36 mmHg to 4 mmHg after the stent placement.The intracranial hypertensive svmotoms resolved and one month later,the CSF opening pressure decreased to 14 cmH2O.

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