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HOX genes in the skin

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Author:
No author available
Journal Title:
CHINESE MEDICAL JOURNAL
Issue:
18
DOI:
10.3760/cma.j.issn.0366-6999.2010.18.021
Key Word:
HOX genes;skin development;skin regeneration;wound healing

Abstract: @@ Deep skin wounds heal by scar formation with a loss of its original appearance, structure and function.However, when the same damage occurs to the skin of an early gestational fetus, complete regeneration can be observed. Despite significant research in the field of skin regeneration, many mysteries remain, such as the loss of wound healing ability with maturity, the differences in healing at different parts of the body, and the presence of hypertrophic scars and keloids in some races but not in others. The finding of HOX genes in the skin provides new explanations to these conundrums.

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