Evaluation of therapeutic effects with inlra ( Need to be modified by authors ) -operative iodine-125 seed implantation for advanced pancreatic carcinoma

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Author:
ZHUANG Li-Ming(Department of Oncosurgery,Affiliated Quanzhou First Hospital of Fujian Medical University, Quanzhou 362000, China)
SU Zi-jian()
WANG Cong-ren()
PAN Qun-xiong()
ZHUANG Jian-liang()
Journal Title:
Journal of Chinese Physician
Issue:
Volume 14, Issue 03, 2012
DOI:
10.3760/cma.j.issn.1008-1372.2012.03.002
Key Word:
Pancreatic neoplasms/RT;Brachytherapy;Iodine isotopes/TU

Abstract: Objective To analyze the clinical effects of internal radiation of iodine-125 seed implantation in the treatment of advanced pancreatic carcinoma.Methods 22 patients with unresectable and advanced pancreatic carcinoma were treated by the internal and interstitial radiation using iodine-125 seed implantation.Results Survival of 20 months was observed in 5 patients,10 ~ 20 months in 9 patients,2 ~10 months in 8,patients with an average of (13.47 ± 8.12) months.Among the 22 patients,complete response was obtained in 5 patients,partial response in 8 patients,no response in 7 paticnts,and the other showing PD.The response rate( CR + PR) was 59%.Conclusions Intra - operative internal radiation by iodine - 125 seed implantation does show some therapeutic effects for advanced pancreatic carcinoma.

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