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Application value of percentage of pulmonary perfusion defect scores in predicting risk stratification of acute pulmonary embolism

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Author:
No author available
Journal Title:
Journal of Chinese Physician
Issue:
9
DOI:
10.3760/cma.j.issn.1008-1372.2011.09.003
Key Word:
肺栓塞;肺动脉;灌流;危险性评估;预后;Pulmonary embolism;Pulmonary artery;Perfusion;Risk assessment;Prognosis

Abstract: Objective To investigate the clinical value of percentage of pulmonary perfusion defect score ( PPDs% ) for risk stratification and prognosis evaluation in patients with acute pulmonary embolism (APE).Methods A retrospective study was carried out on PPDs% data of patients( n =21 ) with confirmed APE from January 2001 to December 2008.The patients were divided into three levels,low( n =10),medial( n =7) and high risk groups( n =4),according to 2008 ESC APE diagnosis and treatment guidelines.The reference index in predicting risk stratification by PPDs% was ascertained.34 patients with confirmed APE were divided into three levels ( mild,moderate and severe risk levels) according to the standard of PPDS% diagnosis from January 2009 to June 2011.A prospective study on the incidence rate of the clinical adverse events was performed.Results The PPDs% of low,medial and high risk levels according to 2008 ESC guidelines were (25.94 ± 3.95 ) %,(45.63 ± 4.38 ) % and ( 58.42 ± 4.96 ) % respectively,with a significant difference ( t ≥4.755,P < 0.01 ).The standard of PPDS% diagnosis for risk stratification was confirmed in APE:low risk levels:PPDs% < 30%,moderate:30% ≤ PPDs% <50%,and high:PPDs% ≥50%.The mild,moderate and severe risk patients with APE were 17cases,11cases and 6cases respectively,according to the standard of PPDs% diagnosis,or 15cases,13cases and 6cases respectiveldy,according to the standard of 2008 ESC guidelines.The uniform rate was 94.11% for two methods; the uniform rate was 100.00% in which high risk of APE.The mild,moderate and severe risk patients with APE according to the standard of PPDs% standard with clinical adverse events for were 1case (5.89% ),3cases (27.27% ) and 4cases (66.67% ) respectively,with a significant difference ( x2 =9.23,P <0.01 ).Conclusions PPDs% could be used as an important reference index for risk stratification of diagnosis,selecting therapeutic programs,evaluating therapeutic efficiency and predicting the prognosis in patients with APE.

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