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Study of the relationship between blood - fat abnormality and plasma fibrinolytic activity in patients with atherosclerotic cerebral infarction
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- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1008-1372.2007.07.001
- Key Word:
- 脑梗塞;动脉硬化;脂类;纤维蛋白溶解
Abstract： 目的 探讨动脉硬化性脑梗死患者(ACI)的血脂异常与血浆纤溶活性的关系.方法 采用常规方法测定91例ACI患者和40例健康老年人的血脂浓度和血浆t-PA和PAI-1活性.结果 急性和恢复期ACI患者的血清TG、CHO、LDL、ApoB、Lp(a)浓度和血浆PAI-1活性显著高于健康组(P＜0.05～0.01),血清ApoA、HDL浓度和血浆t-PA活性显著低于健康组(P＜0.05～0.01).急性和恢复期ACI患者的血清TG、LDL、ApoB、Lp(a)浓度与血浆PAI-1活性正相关(r=0.28,P＜0.05;r=0.60,P＜0.01;r=0.22,P＜0.05;r=0.24,P＜0.05;r=0.23,P＜0.05;r=0.21,P＜0.05;r=0.26,P＜0.05;r=0.67,P＜0.01),与血浆t-PA活性不相关.结论 ACI患者血清TG、LDL、ApoB、Lp(a)浓度的增高降低血浆纤溶活性.
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