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Expression and implication of DDH and VEGF in the tissue of NSCLC
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- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1008-1372.2007.03.005
- Key Word:
- 癌,非小细胞肺;血管内皮生长因子类;醇脱氢酶
Abstract： 目的 研究二氢二醇脱氢酶(DDH)与血管内皮生长因子(VEGF)在非小细胞肺癌(NSCLC)中的表达情况,探讨两者与NSCLC的关系.方法 运用免疫组化方法检测42例NSCLC手术标本中DDH与VEGF的表达.结果 DDH与VEGF在NSCLC组织中的阳性表达率(83.3%、81.1%)较癌旁组织(34.4%、31.2%)与良性肿瘤(12.5%、18.7%)明显增强(P＜0.05);且与淋巴结转移和临床分期有关(P＜0.05).结论 DDH与VEGF高表达可能与NSCLC发生发展有关.
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