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Effects of diagnostic transabdominal ultrasound on human villi
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- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 9
- DOI:
- 10.3760/cma.j.issn.1008-1372.2006.09.001
- Key Word:
- 超声检查/副作用;妊娠初期;绒毛膜绒毛
Abstract： 目的 通过诊断性超声对人早孕绒毛组织超微结构及凋亡相关蛋白的研究,探讨诊断性超声对人早孕绒毛组织的安全性问题.方法 选取健康早孕而自愿终止妊娠的妇女35例,随机分组,不同时间的经腹部诊断性超声波作用后行人工流产取绒毛组织,透射电镜观察其超微结构,同时半定量RT-PCR分析绒毛组织中Caspase-3 mRNA和Livin mRNA的表达.结果 5 min组与正常组比较无明显的超微结构变化,而15 min组与正常组比较呈现较明显的变化.同时在不同辐照时间下Caspase-3 mRNA的表达,10 min组和15 min组与正常组比较差异有统计学意义(P＜0.05);LivinαmRNA的表达与正常组比较差异有统计学意义(P＜0.05);LivinβmRNA的表达与正常组比较差异无统计学意义(P＞0.05).结论 常规剂量的经腹部诊断性超声对早孕绒毛组织是安全的.
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