You Position: Home > Paper
The Study of Relationship Between Apolipoprotein H and Serum Lipid in Patients with Cerebral Infarction
( views:181, downloads:8 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1008-1372.2002.01.003
- Key Word:
- 脑梗死;载脂蛋白H;血脂
Abstract： 目的观察脑梗死患者血清载脂蛋白(ApoH)水平与血脂的相关性,探讨ApoH与脑梗死的关系.方法:放免法测定ApoH血清水平,ELISA 法测定Lp(a)水平,免疫比浊法测定ApoA-1和ApoB,酶法测定HDL、LDL、TG、TC.结果脑梗死患者血清ApoH水平显著高于卒中危险因素对照组和正常对照组(P＜0 .05),且ApoH的水平与 TC、LDL呈正相关(γ＝0.52,P＜0.01,γ＝0.49,P ＜0.05),与TG、Lp(a)无相关性.结论脑梗死患者血清ApoH血清水平与 TC、LDL相关,ApoH可能通过干扰脂质代谢,在脑梗死的发生发展过程中起一定的作用.
- [1]顾云,王绿娅.冠心病和脑梗塞患者载脂蛋白B基因多态性研究[J].1999,(1).
- [2]李家增，贺石林，王鸿利主编.血栓病学[M].1998.
- [3]Maurizio Cassader,Gianluca Ruiu,Roberto Gambino,etc.Apolipoprotein H levels in diabetic subjects: Correlation with cholesterol levels[J].1997,46(5).
- [4]T. McNally,M. Crook,I. J. Mackie,etc.β2glycoprotein-I antigen is increased in primary hyperlipidaemia[J].1994,88(2).
- [5]I, Schousboe.beta 2-Glycoprotein I: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway.[J].1985,66.