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The Levels and Significance of IL - 8, IL - 12, NO in the Sera of Patients with Primary Hepatocellular Carcinoma

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Author:
No author available
Journal Title:
JOURNAL OF CHINESE PHYSICIAN
Issue:
8
DOI:
10.3760/cma.j.issn.1008-1372.2000.08.007
Key Word:
原发性肝癌;白细胞介素-8;白细胞介素-12;一氧化氮

Abstract: 为探讨原发性肝癌患者机体内免疫细胞功能状况以及与肿瘤细胞之间的关系,检测了38例原发性肝癌,33例肝炎后肝硬化,30例健康对照组血清中白细胞介素-8(IL-8),白细胞介素-12(IL-12),一氧化氮(NO)水平.结果表明:肝硬化组三项指标均显著升高(P<0.05),肝癌组IL-8升高显著,IL-12和NO水平无显著升高,认为此与肝癌患者机体内巨噬细胞存在严重功能障碍有关,动态检测三项指标对原发性肝癌有辅助诊断价值.

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