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Effects of Cimetidine on the Erythrocyte Immune Function and Interleukin- 2 in Patients with Obstructive Jaundice after Bililary Drainage
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- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 8
- DOI:
- 10.3760/cma.j.issn.1008-1372.2000.08.006
- Key Word:
- 梗阻性黄疸;红细胞免疫;白细胞介素2;西咪替丁*
Abstract： 为研究西咪替丁对梗阻性黄疸患者行胆道引流术后红细胞免疫功能及IL-2的调节作用,采用红细胞酵母菌花环法、放免分析法,分别检测非西咪替丁组和西咪替丁组的红细胞C3b受体花环率(RBC-C3b RR)、红细胞免疫复合物花环率(RBC-ICR)及IL-2活性.结果显示梗阻性黄疸患者RBC-C3bRR、IL-2活性降低,RBC-ICR升高;西咪替丁组术后RBC-C3bRR、RBC-ICR及IL-2活性与同时间非西咪替丁组比较差异有显著性(P＜0.05或P＜0.01).说明西咪替丁可促进梗阻性黄疸患者受损的红细胞免疫功能及IL-2活性的恢复,这对于降低梗阻性黄疸患者感染发生率具有一定价值.
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