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Significance of Detecting the Function of Renal Tubules in Estimating the Development of Primary Glomerular Disease(PGD)
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- Author:
- No author available
- Journal Title:
- JOURNAL OF CHINESE PHYSICIAN
- Issue:
- 8
- DOI:
- 10.3760/cma.j.issn.1008-1372.2000.08.004
- Key Word:
- 肾小球疾病;病理变化;肾功能试验
Abstract： 为探讨肾小管功能检测在评价原发性肾小球疾病(PGD)进展中的意义,采用ELISA法、生化方法及肾间质病理计量分析法对48例原发性肾小球疾病患儿分别检测肾小管功能(尿RBP、尿β2-MG、尿微量A1b、尿NAG酶)和肾间质病理改变.结果发现:(1)肾脏病理损害程度与肾间质损害有关;(2)所有病例均有不同程度的肾间质损害及肾小管功能的异常;(3)肾小管功能改变与肾间质损害程度有正相关关系;显示肾小管功能检测对评价原发性肾小球疾病进展及肾间质损害程度具有重要的临床意义.
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