You Position: Home > Paper

The short-term prognosis for hospitalized acute myocardial infarction patients : the impact of complication by community-acquired pneumonia

( views:334, downloads:24 )
Author:
No author available
Journal Title:
Chinese Critical Care Medicine
Issue:
12
DOI:
10.3760/cma.j.issn.1003-0603.2011.12.001
Key Word:
心肌梗死,急性;社区获得性肺炎;预后;Acute myocardial infarction;Community acquired pneumonia;Prognosis

Abstract: Objective To analyze the correlation between the complication by community-acquired pneumonia(CAP)and the short-term prognosis in hospitalized acute myocardial infarction(AMI)patients.Methods Five thousand five hundred and twenty-four AMI patients hospitalized in the PLA General Hospital from January 1993 to December 2009 were enrolled for clinical data,incidence of complications and 30-day mortality.The data from patients with and without CAP complications were compared.Multivariate logistic regression analysis was employed to assess the impact of CAP on the short-term prognosis of these patients.Results In all 5 524 AMI patients studied,477 cases of CAP was found(8.6%).In comparison with those without CAP complication,these patients had higher age(74.3± 6.5 vs.67.8± 4.5).The incidence of comorbidities[including old myocardial infarction(20.8% vs.11.5%),hypertension(54.3% vs.48.9%),diabetic mellitus(32.7% vs.22.6%),cerebral-vascular disease(8.2% vs.3.5%),chronic renal dysfunction(10.5% vs.3.0%)],and complications[including arrhythmia(8.8% vs.4.6%),gastrointestinal bleeding(5.0% vs.0.8%)and shock(8.6% vs.3.1%)]were all significantly higher,and hyperlipidemia(18.9% vs.30.6%)was significantly lower(P<0.05 or P<0.01)in CAP complicated patients.The 30-day mortality was also significantly higher(32.1% vs.9.7%,P<0.01).Multivariate logistic regression analysis identified CAP and chronic renal dysfunction as an independent predictor of short-term mortality[odds ratio(OR)of CAP 3.693,95 % confidence interval(95 %CI)2.340~5.829,P< 0.01; OR of chronic renal dysfunction 12.608,95%CI 4.448 ~ 35.739,P<0.01].Conclusions The incidence of CAP complication was higher in AMI patients with higher age.CAP complicated patients were more likely to develop comorbidities/complications,and had higher short-term mortality.CAP was an independent risk factor of short-term mortality.

WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn