Abstract: Objective To satisfy the requirements of pre-hospital and first aid at scene for critical patient, rapid transportation, and nonstop treatment in hospital, this paper describes a design of a stretcher integrated first-aid system (SIFAS), which can provide seamless link between pre-hospital and in-hpspital first aid. Methods With the requirements of integration and informationization, related functional modules of the former invented SIFAS were redesigned with principle of miniaturization. Adhering to the principle of best man-machine performance, systemic structural characteristic was studied. Aiming at achieving the best maneuverability but with lightest weight, the materials and processing technology of the framework were modified and improved. Results The SIFAS designed possessed good flexibility, it could be carried on pushed, and it could be attached to many carriers, with shortened time, and continuous first aid could be realized, and waiting time for first aid was greatly reduced. Conclusion The SIFAS provides a possibility for establishing a emergency green path for pre-hospital and in-hospital first aid, and it improves emergency of the patient and quick response of relevant medical institutions.