Abstract： Objective Assessment of outcomes and outcome-related factors of in-hospital cardiopul-monary resuscitation (CPR) based on the " Utstein Style". Methods The study was designed as a prospective, single-institution, registry investigation of 463 patients (included adult and pediatric patients) for whom a CPR was attempted. Results The study population consisted of 320 (69.1 %) male patients and 143 (30. 9%) female patients. The age range of 45- 54, 55- 64, 65- 74 were ranked the first, the second and third highest. In the past medical history, cardiovascular disease and cerebrovascular disorder were two main disorders, accounting for 36. 30% (168/463) and 9. 9% (46/463), respectively. Ventricular fibrillation (VF) was the initial electrocardiographic (ECG) change in 74 patients (16.0%). Two hundred and seventy-three patients received the in-hospital CPR, and 190 patients received the pre-hospital CPR. Spontaneous circulation returned in 34. 6% (160/273) of the in-hospital patients after CPR, and 16. 60% (77/273) survived for 24 hours and 10. 4% (48/273) survived up to the time of discharge. The rates of restoration of spontaneous circulation (ROSC) and survival of the in-hospital CPR were higher than those of the pre-hosptial CPR [47. 6% (130/273) vs. 15. 8% (30/190), 13. 9% (38/273) vs. 5. 3% (10/190), both P<0. 013. Conclusion Prospective "Utstein Style" data collection for CPR is proved to be a valuable tool for the evaluation of management and outcome following in-hospital cardiopulmonary arrest, but the rate of survival for in-hospital resuscitation still seems to be too low. The further improvement of CPR outcome is necessary.