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Impact of chronic anemia on in -hospital clinical outcome of revascularization in patients with coronary artery disease
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- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 11
- DOI:
- 10.3760/j.issn:1003-0603.2007.11.001
- Key Word:
- 贫血,慢性;经皮冠状动脉介入治疗;冠状动脉旁路移植术;血运重建
Abstract： 目的 评价慢性贫血对冠心病患者血运重建术后院内临床结果的影响.方法 选择2002年7月-2004年6月在首都医科大学附属北京安贞医院接受血运重建治疗(经皮冠状动脉介入治疗或冠状动脉旁路移植术)的3 679例患者,按照世界卫生组织确定的贫血标准(血红蛋白:男性＜120 g/L,女性＜110 g/L)将患者分为贫血和非贫血两组.比较两组患者血运重建术后院内不良心脑血管事件(MACCE)的发生率(包括全因死亡、新发心肌梗死、卒中和再次血运重建),并分析其可能的原因.结果 3 679例患者中有贫血患者426例(占11.6%),非贫血患者3 253例(占88.4%).贫血组与非贫血组分别有10例(2.4%)和64例(1.9%)发生院内死亡(P＜0.05);贫血组院内MACCE的发生率明显高于非贫血组(4.2%比3.2%,P＜0.05),但两组新发心肌梗死(0.7%比0.6%)、卒中(1.2%比0.4%)和再次血运重建(0比0.2%)的发生率差异无统计学意义(P均＞0.05).结论 合并贫血的冠心病患者较非贫血患者血运重建术后院内MACCE发生率增加,其中全因病死率的增加更为显著.
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