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Effect of growth hormone on non-protein respiratory quotient and oxidation rate of protein after burn injury
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- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 7
- DOI:
- 10.3760/j.issn:1003-0603.2005.07.005
- Key Word:
- 烧伤;代谢;生长激素;非蛋白呼吸商
Abstract： 目的探讨烧伤后应用生长激素治疗对蛋白质、脂肪、糖三大营养物质代谢的影响.方法将16只背部35%总体表面积Ⅲ度烧伤小型猪随机分为生长激素治疗组和对照组,伤前及伤后24、48、96 h和7、12 d用代谢车测定蛋白质氧化率及非蛋白呼吸商(NPRQ)的变化.结果小型猪烧伤后蛋白质氧化率缓慢升高,NPRQ明显降低,生长激素治疗组NPRQ的降低幅度明显高于非生长激素治疗组,但两组蛋白质氧化率比较差异无显著性.结论烧伤后应用生长激素对机体物质代谢的调节方式主要为内源性脂肪分解增强,对蛋白质的分解无明显影响,但加重了糖的利用障碍.
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