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Clinical study of plasma substitute(Gelofusion) on fluid resuscitation in patients with burned shock
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- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1003-0603.2003.05.003
- Key Word:
- 烧伤;休克;复苏;血浆代用品
Abstract： 目的:验证血浆代用品(血定安)在烧伤休克液体复苏中的临床疗效.方法:20例烧伤总体表面积(TBSA)大于40%且因延迟复苏导致休克的烧伤患者,随机分为血定安复苏组(血定安组,n=11)和血浆复苏组(血浆组,n=9)进行复苏,观察休克期心排血量(CO)、氧供给(DO2)、血细胞比容、血液黏度、血浆黏度、乳酸(LA)含量及碱缺失(BD)等血流动力学、血液流变学及氧代谢指标的变化.结果:快速补液2 h后,CO和DO2显著升高(P<0.05或P<0.01),血细胞比容、血液黏度、血浆黏度、LA和动脉血BD显著下降(P<0.05或P<0.01).两组间比较,伤后24 h内血定安组补液后血浆黏度显著低于血浆组(P均<0.05),其余指标无显著性差异(P均>0.05).结论:在烧伤后休克复苏中,血浆代用品血定安与血浆的疗效相近,可以在烧伤休克早期救治中广泛应用.
- [1]闫柏刚,杨宗城,黄跃生,等.血浆代用品（血定安）应用于烧伤休克复苏的实验研究[J].2001,(2).
- [2]王钦存,肖南,刁有芳,等.未控制出血性休克早期液体复苏的实验研究[J].2002,(12).
- [3]姚咏明,盛志勇.脓毒症研究的若干新动态[J].2000,(6).
- [4]R H, Demling,G C, Kramer,R, Gunther,etc.Effect of nonprotein colloid on postburn edema formation in soft tissues and lung.[J].1984,95.
- [5]J. M. SADDLER,P. J. HORSEY.The new generation gelatins: A review of their history, manufacture and properties[J].1987,42(9).
- [6]Botha AJ,Moore EE,Kim FJ,etc.Postinjury neutrophil priming and activation: an early vulnerable window.[J].1995,118(2).
- [7]A, Sauaia,F A, Moore,E E, Moore,etc.Early predictors of postinjury multiple organ failure.[J].1994,129.