You Position: Home > Paper
Study on difference of injury sensitivity of gastrocnemiu s muscle and intestine after hemorrhagic shock and resuscitation
( views:248, downloads:0 )
- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1003-0603.2002.05.002
- Key Word:
- 休克,失血性;复苏;血流量;氧代谢
Abstract： 目的:探讨腓肠肌和肠组织对缺血、缺氧损伤敏感性的差异.方法:采用Wistar大鼠失血性休克及复苏模型,随机分为6组:假手术对照组,休克90分钟组,休克90分钟复苏0.5、1、2和6小时组;进行腓肠肌和肠组织血流量和氧代谢的检测.结果:失血性休克90分钟,腓肠肌组织血流量降低程度重于肠组织,且复苏后血流量回升的速度慢于空肠、回肠和结肠;复苏后2小时各组织氧耗和氧摄取率明显降低, 肠组织降低程度重于腓肠肌.结论:失血性休克及复苏后肠组织血流量降低程度虽轻于腓肠肌,但对氧的摄取和利用能力低于腓肠肌,这与肠组织对缺血、缺氧损伤敏感性较高有关.
- [1]姜澜,赵秀梅,田牛,等.小肠绒毛微循环的血流动力学体外研究[J].1999,(1).
- [2]Asensio JA,Berne TV,Shoemaker WC,etc.Invasive and noninvasive monitoring for early recognition and treatment of shock in high-risk trauma and surgical patients.[J].1996,76(4).
- [3]R, Tokyay,S T, Zeigler,D L, Traber,etc.Postburn gastrointestinal vasoconstriction increases bacterial and endotoxin translocation.[J].1993,74(4).
- [4]Nalesnik MA,Borle AB,Schraut WH,etc.Oxygen free radical content and neutrophil infiltration are important determinants in mucosal injury after rat small bowel transplantation.[J].1996,62(2).
- [5]Kaushik, Parthasarathi,Herbert H, Lipowsky.Capillary recruitment in response to tissue hypoxia and its dependence on red blood cell deformability.[J].1999,277(6).