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Clinical study of urokinase interventional thrombolysis in the treatment of acute cerebral infarction
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- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1003-0603.2002.01.003
- Key Word:
- 脑梗死,急性;尿激酶;介入溶栓
Abstract： 目的:探讨尿激酶(UK)介入溶栓治疗急性脑梗死的疗效及并发症.方法:采用Selding′s技术经皮穿刺股动脉,将介入导管置入病灶侧颈内动脉行数字减影(DSA)脑血管造影,经介入导管将(40～80)×104 U的UK缓慢灌注30分钟,1小时后重复行DSA脑血管造影;术后静滴UK(5～10)×104 U,每日1次,连续14日.结果:血管完全再通2例,部分再通4例,血流量增加6例,再通率50%.临床疗效评价:治疗后5日、14日神经功能缺损评分和生活能力状况与治疗前比较均有显著性差异(P<0.05和P<0.001);治疗后5日显著进步4例,进步6例,无变化2例;治疗后14日显著进步8例,进步4例;治疗后14日与治疗后5日相比临床疗效有显著性差异(P<0.05).并发症:合并脑出血1例,血管再闭塞1例.结论:对急性脑梗死患者于72小时以内尽早用UK介入溶栓治疗疗效好,不良反应小,安全可靠.
- [1]P D, Lyden,J C, Grotta,S R, Levine,etc.Intravenous thrombolysis for acute stroke.[J].1997,49.
- [2]J V, Byrne.Interventional neuroradiology: an emerging subspeciality.[J].1997,52(12).
- [3]Hacke W.,Zeumer H.,Ferbert A.,etc.Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease[J].1988.
- [4].各类脑血管疾病诊断要点[J].1996,(6).