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High frequency partial liquid ventilation in the treatment of inhalation injury
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- Author:
- No author available
- Journal Title:
- CHINESE CRITICAL CARE MEDICINE
- Issue:
- 12
- DOI:
- 10.3760/j.issn:1003-0603.2001.12.003
- Key Word:
- 高频部分液体通气;肺损伤,吸入性;氟碳;氧合作用
Abstract： 目的:观察高频部分液体通气治疗吸入性肺损伤的效果,并与单纯高频喷射通气的疗效比较.方法:将16只犬经蒸气吸入造成吸入性肺损伤模型,并随机分为对照组和治疗组.2组动物致伤后均行高频喷射通气,治疗组动物同时经气管导管将氟碳液体(3 ml/kg)缓慢注入肺内,实行高频部分液体通气治疗,于30、60及90分钟测定动脉血气、肺顺应性和气道阻力.结果:治疗组动脉血氧分压(PaO2)进行性上升,各时间点与致伤后比较均有显著性差异(P 均 <0.05),动脉血二氧化碳分压(PaCO2)也逐渐增高,于60和90分钟显著高于致伤后水平(P均<0.05) ;与对照组比较,治疗组各时间点的PaO2稍有升高,而PaCO2于90分钟显著增高( P <0.05).在各时间点的动、静态气道阻力和动、静态肺顺应性,2组比较均无明显差异 .结论:高频部分液体通气与单纯高频喷射通气相比,更有利于动脉血氧合,但也有轻度 CO2潴留现象.
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