Abstract： Objective To investigate the efficacy of laparoscope complete mesocolic excision (CME) for right colon cancer.Methods The clinical data of 49 cases of right colon cancer without metastasis and intestinal obstruction who underwent elective laparoscope CME by the same group of surgeons between October 2009 and June 2011 at the First Hospital of Jilin University were analyzed retrospectively.Results Among the 49 cases with CME,the median number of total lymph node retrieved was 22.The positive rate of lymph node in patients with stage Ⅲ disease was 16.3％.The median operative time of all the cases was 145 min.The mean intraoperative blood loss was 75 ml.The median time to flatus passage and defecation was 3 days and 6 days respectively.The median hospital stay was 12 days.The overall postoperative complication rate was 12.2％ (6/49).Conclusion Laparoscope complete mesocolic excision for right colon cancer is safe and feasible.