Comparative study of endoscopic musoucal resection with transparent cap and endoscopic multiband mucosectomy for early esophageal cancer and precancerous lesion

( views:303, downloads:0 )
Author:
ZHANG Yue-ming(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
ZHANG Lei(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
YU Gui-xiang(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
JU Feng-huan(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
XUN Hua-ying(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
ZHU Na(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
WANG Gui-qi(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
HE Shun(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
XUE Li-yan()
LV Ning()
CHENG Gui-yu()
QIN Xiu-min(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
DOU Li-zhou(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
LAI Shao-qing(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
NI Xiao-guang(Department of Endoscopy, Cancer Hospital & Institute, Chinese Academy of Medical Sciences,Beijing 100021, China)
Journal Title:
Chinese Journal of Gastrointestinal Surgery
Issue:
Volume 15, Issue 09, 2012
DOI:
10.3760/cma.j.issn.1671-0274.2012.09.012
Key Word:
Esophageal neoplasms; Precancerous lesions; Endoscopic musoucal resection with transparent cap; Endoscopic multi-band mucosectomy

Abstract: Objective To evaluate the efficacy and safety of endoscopic musoucal resection with transparent cap (EMR-Cap) and endoscopic multi-band mucosectomy (MBM) in the treatment of early esophageal cancer and precancerous lesion.Methods A retrospective study was performed to review 30 EMR-Cap cases from December 2008 to December 2009 and 32 MBM cases from January 2010 to January 2011 of early esophageal cancer and precancerous lesions.The differences between these two techniques in efficacy,safety,and cost were compared.Results In EMR-Cap group,the median resection time was 26 (10-56) min and median procedure time was 43 (22-81) min,significantly longer than those in MBM group [ 10 (7-18) min and 32 (28-45) min,P=0.036 and 0.038,respectively].There were no significant differences between the two groups in total thickness and depth of resected lesions (P>0.05).In EMR-Cap group,the median cost was significantly higher than that of MBM group [(5466±354) vs.(4014±368) RMB,P=0.008)].Conclusions EMR-Cap and MBM are minimally invasive,safe and effective methods in the treatment of early esophageal cancer and precancerous lesions.Compared to the EMR-Cap,MBM is simple with shorter treatment time and lower cost.

  • [1]National Comprehensive Cancer Network.NCCN Clinical Practice Guidelines in Oneology:esophageal and esophagogastric junction cancers.V.2.2011.http://www.nccn.org/professional/physician_gls/pdf.
  • [2]Endoscopic Classification Review Group.Update on the paris classification of superficial neoplastic lesions in the digestive tract.Endoscopy,2005,37(6):570-578.
  • [3]王贵齐,魏文强,郝长清,等.早期食管癌及其癌前病变内窥镜透明帽法食管黏膜切除术.中华医学杂志,2003,83(4):306-308.
  • [4]Participants in the Paris Workshop.The Paris endoscopic classification of superficial neoplastic lesions:esophagus,stomach,and colon:November 30 to December 1,2002.Gastrointest Endosc,2003,58 (6 Suppl):S3-S43.
  • [5]Satodate H,Inoue H,Yoshida T,et al.Circumferential EMR of carcinoma arising in Barrett's esophagus:case report.Gastrointest Endosc,2003,58 (2):288-292.
  • [6]Mizuta H,Nishimori l,Kuratani Y,et al.Predictive factors for esophageal stenosis after endoscopic submucosal dissection for superficial esophageal cancer.Dis Esophagus,2009,22 (7):626-631.
  • [7]Fujishiro M,Yahagi N,Kakushima N,et al.En bloc resection of a large semicircular esophageal cancer by endoscopic submucosal dissection.Surg Laparosc Endosc Percutan Tech,2006,16(4):237-241.
  • [8]Katada C,Muto M,Manabe T,et al.Esophageal stricture after endoscopic mucosal resection of superficial esophageal lesions.Gastrointest Endosc,2003,57(2):165-169.
  • [9]Lewis JJ,Rubenstein JH,Singal AG,et al.Factors associated with esophageal stricture formation after endoscopic mucosal resection for neoplastic Barrett's esophagus.Gastrointest Endosc,2011,74 (4):753-760.
  • [10]Nonaka K,Arai S,Ishikawa K,et al.Short term results of endoscopic submucosal dissection in superficial esophageal squamous cell neoplasms.World J Gastrointest Endosc,2010,2(2):69-74.
  • [11]Repici A,Hassan C,Carlino A,et al.Endoscopic submucosal dissection in patients with early esophageal squamous cell carcinoma:results from a prospective Western series.Gastrointest Endosc,2010,71 (4):715-721.
  • [12]Park YM,Cho E,Kang HY,et al.The effectiveness and safety of endoscopic submucosal dissection compared with endoscopic mucosal resection for early gastric cancer:a systematic review and metaanalysis.Surg Endosc,2011,25(8):2666-2677.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn