Abstract: Colorectal cancer has become one of the most common malignant tumors that affects Chinese's health.Recurrence and metastasis are main reasons for death of colorectal cancer patients. Making up individualized and comprehensive therapeutic strategy according to patients' specific matters is the developmental direction of diagnosis and treatment for colorectal cancer.Only if standardize clinical pathway,perfect postopertlve follow-up system,and accelerate research development on biomarkers,individualized therapy of colorectal cancer can be accomplished.