Abstract： Objective To evaluate the risk factors of postoperative complications after reoperation for recurrent Crohn disease (CD). Methods From 1995 to 2009, 65 patients undergoing reoperation for recurrent CD were identified in the First Affiliated Hospital of Fujan Medical University.Risk factors of postoperative complications were analyzed. These patients were matched by age to 65 patients undergoing primary operation and treatment outcomes were compared between primary operation and reoperation. Results Postoperative complications were observed in 25 cases (38.5%) undergoing reoperation for CD recurrence and the rate of postoperative complication was higher than that after primary operation (12.3%). Postoperative complications rate in patients with stoma was significantly lower than those without stoma (15.8% vs. 47.8%, x2=5.831, P=0.016). Compared to primary operation, reoperation had longer operative time, more severe intraperitoneal adhesion, and a longer postoperative hospital stay (all P＜0.05). Conclusion Reoperation for CD recurrence is associated with higher postoperative complications. Temporary stoma may decrease the rate of postoperative complication.