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Risk factors of operation and reoperation in patients with Crohn disease

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF GASTROINTESTINAL SURGERY

Issue:: 3

DOI:: 10.3760/cma.j.issn.1671-0274.2007.03.004

Key Word:: 克罗恩病;外科手术;再手术;危险因素

Abstract：目的了解我国部分地区治疗克罗恩病(CD)的手术率及再手术率,并评估相关危险因素.方法多中心回顾性分析142例CD患者的手术与再手术情况,并采用多因素分析法对相关危险因素进行评估.结果本组患者手术率64.8%,起病后5年累计手术率为52.0%.手术风险:男性患者高于女性(P＜0.01);40岁以上患者高于20岁以下者(P＜0.05);回肠型及空肠以上型患者高于结肠型患者(P＜0.05,P＜0.01).本组再手术率33.9%,初次术后3年累计复发率为21.0%.再手术风险穿孔型患者高于非穿孔型患者,结肠型及回结肠型患者高于回肠型患者(均P＜0.05).结论半数CD患者在起病5年内需接受手术治疗,其中1/5的患者于术后3年内需接受再次手术.病变位于结肠者具有较高的再手术风险,初次手术适应证为穿孔型者增加再手术风险.

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