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Clinicopathological features and prognosis of 1829 patients with primary colorectal cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1671-0274.2004.06.005
- Key Word:
- 结肠直肠肿瘤;病理学,临床;预后
Abstract： 目的探讨结直肠癌的临床病理特征和预后.方法应用 SPSS 10.0软件对 1991年 1月至 2002年 12月间经手术和病理确诊、且随访资料完整的 1829例结直肠癌患者的临床资料进行统计分析,并通过 Cox回归模型,确立影响预后的独立因素.结果 1829例结直肠癌患者的平均生存时间为 76.8个月, 5年生存率 56.9%.单因素分析结果显示:年龄、出现症状的时间、肿瘤部位、手术性质、病理类型、肿瘤直径、原发肿瘤侵犯深度、淋巴结转移、远处转移和 Dukes分期与预后相关.多因素回归分析显示:肿瘤部位、手术性质、病理类型、肿瘤直径、原发肿瘤侵犯深度、淋巴结转移和 Dukes 分期是影响结直肠癌患者术后生存的独立因素.结论应加强普查和早诊的意识,早期发现、早期诊断和治疗结直肠癌,最大限度地改善患者的生存状况.
- [1]康建物.影响进展期大肠癌切除术后长期生存的高危因素分析[J].2003,(3).
- [2]杨祖立,汪建平,王磊,等.结直肠癌预后的多因素回归分析[J].2003,(3).
- [3]梁寒,郝希山,王晓娜,等.老年人直肠癌患者的预后因素分析[J].2004,(3).
- [4]安大立,李志霞.青年人与中老年人结直肠癌的临床病理及预后对照研究[J].2001,(2).
- [5]蔡三军,管祖庆,徐烨,等.大肠癌伴肝转移患者的预后因素[J].2001,(5).
- [6]黄忠荣.B期大肠癌切除后复发和死亡的高危因素[J].2000,(2).
- [7]Moran,Collins,Gibbs,etc.Survival of patients with colon cancer in Europe: a cautionary tale[J].2000,2(4).
- [8]O, Trabelsi,M, Hassair,K, Haouet,etc.[Colon cancer. Study of 153 cases and comparison with a series of 140 historic cases].[J].1999,77(12).
- [9]Patrick H D, Colquhoun,Steven D, Wexner.Surgical management of colon cancer.[J].2002,4(5).
- [10]Gualtieri N,Adeonigbagbe O,Freiman H,etc.Colorectal carcinoma in young females.[J].2004,97(3).
- [11]Makela J,Laitinen S,Kiviniemi H.Prognostic factors after surgery in patients younger than 50 years old with colorectal adenocarcinoma.[J].2002,49(46).
- [12]Mircea, Diculescu,R?zvan, Iacob,Speran?a, Iacob,etc.The importance of histopathological and clinical variables in predicting the evolution of colon cancer.[J].2002,11(3).
- [13]Olusola Olofinlade,Mokuolu Ao.Colorectal cancer in young patients[J].2001,44(12).
- [14]郝希山, 王殿昌主编.腹部肿瘤学[M].2003.
- [15]T H, Edna,T, Bjerkeset.Perioperative blood transfusions reduce long-term survival following surgery for colorectal cancer.[J].1998,41(4).