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Surgical treatment for patients with gastrointestinal stromal tumor
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1671-0274.2003.05.002
- Key Word:
- 胃肠道间质瘤;外科治疗;预后
Abstract： 目的分析胃肠道间质瘤(gastrointestinal stromal tumor,GIST)外科治疗效果以及影响手术疗效的因素.方法对我院1990年1月至2003年5月外科治疗的97例GIST患者的临床资料和病理切片(含免疫组织化学检查)重新复核并对患者进行随访.结果本组中位生存时间为57.3个月,完全切除术组患者生存率明显优于不完全切除术组(P=0.00),后者无1例生存期超过2年.完全切除术组中,肿瘤局部切除和肿瘤及所在器官切除患者生存率之间比较,差异无显著性意义(P=0.2795);但肿瘤局部切除和肿瘤及所在器官切除两组分别与扩大切除术组比较,差异却有显著性意义(P=0.00).完全切除术患者的生存率与其性别、肿瘤部位和大小、肿瘤性质、核分裂及复发转移有关;但多因素的Cox回归分析显示,其术后生存率仅与肿瘤大小、肿瘤性质和复发转移相关.结论GIST以外科治疗为主,原则上施行局部完全切除即可,广泛切除或扩大淋巴结清扫不能提高其生存率.
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