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The relationship between mdm-2 amplification and gastric cancer,its lymph node metastasis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1671-0274.2000.01.009
- Key Word:
- mdm-2胃癌;淋巴转移
Abstract： 目的探索mdm-2扩增与胃癌及其淋巴转移的关系.方法用DC-PCR技术定量分析32例胃癌及转移灶中mdm-2扩增.结果 mdm-2在转移淋巴结中的扩增频率(57.1%)高于胃原发癌中的扩增频率(37.5%),3例淋巴管内有瘤栓、淋巴结转移阴性的原发癌灶中发现mdm-2扩增.结论 mdm-2扩增与胃癌的淋巴转移关系较密切,它可能成为监测胃癌淋巴转移的潜在性分子标志物.
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- [2]刘复生,王奇璐,果红.恶性肿瘤的扩散与转移[J].1996,(11).