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A control study of curative effects of suture plus PGV or suture plus omeprazole-plan for the treatment of duodenal ulcer with acute perforation
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF GASTROENTESTINAL SURGERY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1671-0274.1999.01.008
- Key Word:
- 十二指肠溃疡;迷走神经切断术;幽门螺杆菌;奥美拉唑
Abstract： 目的研究十二指肠溃疡穿孔的两种不同疗法--穿孔修补术加近侧胃迷走神经切断术(PGV)与穿孔修补术加奥美拉唑方案的临床疗效.方法将1994年1月-1996年12月相继入院的48例十二指肠溃疡穿孔患者随机分为A、B两组.A组(21例)在穿孔修补术的基础上,加行PGV.B组(27例)仅作穿孔修补术,术后辅予奥美拉唑方案(即口服奥美拉唑加羟氨苄青霉素加灭滴灵).术后定期随访.随访结果按Visick标准分级.结果 A组术后半年和2年疗效优良者(VisickⅠ加Ⅱ级)分别为18例(85.7%)和17例(81.0%),溃疡复发者(VisickⅣ级)分别为1例(4.8%半年)和2例(9.5%2年).B组术后半年和2年疗效优良者分别为19例(66.7%)和10例(37.0%),溃疡复发者分别为5例(18.5%)和12例(44.5%).A组疗效优于B组(P＜0.01).Hp检测,A组术后半年和两年的Hp阳性率分别为81.0%和85.7%(P＞0.05);B组分别为18.5%和51.9%(P＜0.01).结论十二指肠溃疡穿孔在施行修补术后,应同时加行PGV,以提高对溃疡病的根治效果.
- [1]B J, Marshall,C S, Goodwin,J R, Warren,etc.Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori.[J].1900,2.
- [2]C P, Dooley,H, Cohen,P L, Fitzgibbons,etc.Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons.[J].1989,321(23).
- [3]F, Mégraud,M P, Brassens-Rabbé,F, Denis,etc.Seroepidemiology of Campylobacter pylori infection in various populations.[J].1989,27.
- [4]D Y, Graham,P D, Klein,A R, Opekun,etc.Effect of age on the frequency of active Campylobacter pylori infection diagnosed by the [13C]urea breath test in normal subjects and patients with peptic ulcer disease.[J].1988,157.
- [5]S, Levi,K, Beardshall,G, Haddad,etc.Campylobacter pylori and duodenal ulcers: the gastrin link.[J].1989,1.
- [6]D Y, Graham,N M, Agrawal,S H, Roth.Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial.[J].1988,2(8623).