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A study of correlation between soluble receptor for advanced glycation end products and retinopathy in type 2 diabetes mellitus
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 3
- DOI:
- 10.3969/j.issn.1006-6187.2012.03.003
- Key Word:
- 可溶性糖基化终产物受体;糖尿病,2型;视网膜病变
Abstract： 目的 探讨血清可溶性糖基化终产物受体(sRAGE)与T2DM视网膜病变的关系. 方法 将69例T2DM患者分成DR组和无DR(NDR)组,25名健康体检者为正常对照(NC)组.分别检测sRAGE浓度、BMI、FPG、血脂和HbA1c,并记录糖尿病病程和有无高血压病. 结果 One-way ANOVA显示DR组sRAGE显著低于NC组和NDR组(P＜0.01),NDR组与NC组无显著差异(P＞0.05).Logistic回归分析显示sRAGE是DR的重要保护因素(P＜0.05). 结论 sRAGE可能是DR一种新的且有潜在保护作用的因子.
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