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Correlation between blood glucose fluctuation and non-proliferative diabetic retinopathy in patients with type 2 diabetes mellitus
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 3
- DOI:
- 10.3969/j.issn.1006-6187.2012.03.002
- Key Word:
- 糖尿病,2型;动态血糖监测;非增生性视网膜病变
Abstract： 目的 探讨T2DM患者血糖波动特征与非增生性视网膜病变的相关性. 方法 选取T2DM非增生性视网膜病变(NPDR)组97例；糖尿病正常眼底(NDR)对组照100例.采用动态血糖监测系统(CGMS)监测两组72h血糖变化. 结果 NPDR组血糖标准差(SDBG)、最大血糖波动幅度(LAGE)、平均血糖水平(MBG)明显高于NDR组(P＜0.05)；NPDR与年龄、病程、SBP、DBP、HbA1c、SDBG、LAGE、MBG呈正相关(P＜0.05),与HDL-C、2hC-P呈负相关(P＜0.05).偏相关分析显示NPDR与SDBG呈正相关(r=0.325 P=0.000). 结论 血糖波动与T2DM非增生性视网膜病变的发生发展相关.
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