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Relationship between Peripheral Arterial Disease and Chronic Kidney Disease in Type 2 Diabetic Patients
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 2
- DOI:
- 10.3969/j.issn.1006-6187.2012.02.005
- Key Word:
- 糖尿病,2型;慢性肾脏病;外周动脉病变;危险因素
Abstract： 目的 探讨T2DM患者中慢性肾脏病(CKD)及外周动脉病变(PAD)的相关性 方法 横断面研究501例住院T2DM患者.以踝臂指数(ABI)＜0.9定为PAD,肾小球滤过率(GFR)＜60 ml·min-1·(1.73 m2)-1定为CKD,尿白蛋白排泄率(UAER)≥20 μg/min定为微量白蛋白尿. 结果 35.7％患者GFR＜60 ml·min-1·(1.73 m2)-1,61.5％有微量白蛋白尿.与对照组相比,ABI＜0.9的糖尿病患者CKD的患病率更高(58.9％vs29.4％,P＜0.01).调整传统危险因素后,CKD和微量白蛋白尿是ABI＜0.9的独立危险因素. 结论 T2DM患者GFR＜60 ml·min-1·(1.73 m2)-1和微量白蛋白尿与PAD的发生独立相关,在具有CKD及微量白蛋白尿的T2DM人群中并发PAD的比例增加,应对这一高危人群进行PAD的进行早期诊断及治疗.
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