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Effect of insulin detemir as add-on therapy to previous oral anti-diabetes drugs on blood glucose level in type 2 diabetes patients
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 12
- DOI:
- 10.3969/j.issn.1006-6187.2011.12.012
- Key Word:
- 糖尿病,2型;口服降血糖药;HbA1c;地特胰岛素
Abstract： 目的 观察地特胰岛素联合口服降糖药(OAD)对OAD控制不佳的T2DM患者血糖控制的影响. 方法 人选30例口服降糖药效果欠佳的T2DM患者,给予地特胰岛素治疗.分别于治疗前、治疗后12周、治疗后24周测定HbA1c、FBG、体重、BMI. 结果 应用地特胰岛素治疗24周后HbA1c、FBG较治疗前均明显降低(P＜0.05).治疗前后血脂、体重、BMI、腰围、臀围无明显变化.应用地特胰岛素治疗低血糖事件发生率较低,且无夜间低血糖事件.结论 地特胰岛素联合OAD治疗可以改善OAD疗效差的T2DM病情,体重增加不明显,低血糖发生率低.
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