You Position: Home > Paper
Relationship between non-proliferative diabetic retinopathy and the carotid artery intima-media thickness in type 2 diabetic patients
( views:263, downloads:109 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 7
- DOI:
- 10.3969/j.issn.1006-6187.2011.07.012
- Key Word:
- 糖尿病,2型;糖尿病非增生型视网膜病变;颈动脉内膜中层厚度
Abstract： 目的 探讨2型糖尿病(T2DM)患者非增生型视网膜病变(NPDR)与颈动脉内膜中层厚度(IMT)之间的关系.方法 选择NPDR组97例,糖尿病正常眼底(NDR)对组照100例.B超检测IMT.结果 (1)NPDR组IMT明显高于NDR组(P<0.01).(2)NPDR与年龄、病程、收缩压、舒张压、糖化血红蛋白、IMT、尿白蛋白呈正相关(P<0.05),与HDL-C、餐后2h C肽呈负相关(P<0.05).Logistic回归显示IMT是NPDR的主要危险因素(P<0.01).(3)IMT增厚组(60.7%) NPDR发病率明显高于正常组(44.1%)(P<0.05).结论 T2DM合并颈动脉IMT增厚者NPDR发病率显著增高,推测动脉粥样硬化可能是NPDR的一个重要的相关因素.
- [1]李桂芹,杨金奎,李明珠.不同病程中C-肽与2型糖尿病微血管病变的相关性[J].2009,(1).
- [2]Dursun B,Apaydin A,Ozben T,etc.Are uremia, diabetes, and atherosclerosis linked with impaired antioxidant mechanisms?[J].2008,56(2).
- [3]Chew EY,Ambrosius WT,Davis MD,etc.Effects of medical therapies on retinopathy progression in type 2 diabetes.[J].2010,363(3).
- [4]M, Ino-ue,A, Azumi,M, Yamamoto.Ophthalmic artery blood flow velocity changes in diabetic patients as a manifestation of macroangiopathy.[J].2000,78(2).