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The therapeutic effects of a short term CSⅡ treatment of type 2 diabetes patients with hepatitis B virus(HBV) infection
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 6
- DOI:
- 10.3969/j.issn.1006-6187.2011.06.002
- Key Word:
- 糖尿病,2型;乙型肝炎病毒;持续皮下注射胰岛素
Abstract： 目的 分析合并乙肝病毒感染的初诊2型糖尿病患者胰岛素泵短期治疗的效果.方法 回顾性分析曾接受胰岛素泵(CSⅡ)强化治疗2周的初诊2型糖尿病患者的临床特点,包括乙肝病毒感染组26例(HBsAg阳性,乙肝组),与乙肝组HbA1c及年龄、性别、BMI相匹配的对照组52例(HBsAg阴性).结果 与对照组比较,乙肝组空腹血糖相对较低[(9.38±1.09)mmol/L vs(10.46±1.14)mmol/L],餐后2小时血糖较高[(19.61±3.92)mmol/L vs(16.78±3.15)mmol/L],乙肝组胰岛素、HOMA-β也高于对照组(P＜0.05).乙肝组在3月、6月、12月、24月及36月血糖维持达标率均高于对照组(P＜0.05).结论 胰岛素泵治疗后2周停用降糖药物的第3,6,12,24,36周随访血糖达标缓解率乙肝组高于对照组.乙肝病毒感染可能对2型糖尿病患者糖代谢存在影响.
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