Abstract： Objective To study outcome of diabetic foot ulcers and to seek its association with features of the ulcers. Methods Data collected retrospectively were analyzed in a consecutive cohort of 106 patients referred to our hospital between January and November in 2008.A single index ulcer was classified according to potential factors,including age,sex,BMI,duration of diabetes mellitus,duration of diabetic foot,ulcer area,depth,infection,perfusion,osteomyelitis,gangrene and comorbidities. The relationship between the outcome and the factors was analyzed. Results Diabetic foot showed healing in 71 Case,among whom 13 had minor amputation,and unhealing in 35 cases,among whom 5 had major amputation.Age,anemia,depth,infection,osteomyelitis,DPN,gangrene and perfusion were all univariate predictors. In logistic regression analysis， osteomyelitis，gangrene and perfusion were independent predictors of healing failure. In the study of 27 patients without osteomyelitis,gangrene or ischemia, infected ulcers needed more time to heal (P＜0.05). Conclusions Whether ulcers are ischemic or not, infection is an important influential factor. When ulcers are treated in time, ostemoyelitis or gangrene occurs less.