You Position: Home > Paper
Comparison of the efficacy between basal glargine with pre-meal short-effective insulin and continuous subcutaneous insulin infusion (CSII) in type 2 diabetics
( views:462, downloads:245 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 3
- DOI:
- 10.3969/j.issn.1006-6187.2009.03.019
- Key Word:
- 甘精胰岛素;胰岛素泵;强化治疗;糖尿病,2型
Abstract： 目的 探讨甘精胰岛素联合三餐前短效胰岛素和胰岛素泵治疗对口服降糖药效果不佳的2型糖尿病的疗效、安全性及性价比.方法 60例T2DM患者分为甘精胰岛素注射(甘精组)和胰岛素泵(CSII组),两组的年龄、BMI、FC-P,FPG、2hC-P、2hPG、HbA1c差异无统计学意义(P0.05).结果 甘精组和CSII组治疗均有效,FPG、2hPG均较治疗前明显下降,FC-P、2hC-P均较治疗前明显升高(P<0.05).两组达到相同血糖水平所需的治疗时间以及低血糖发生率无统计学差异(P0.05),但甘精组的胰岛素用量明显低于CSII组(P<0.05).结论 甘精胰岛素配合三餐前短效胰岛素能有效模拟人生理胰岛素分泌,有效控制高血糖,且效价比高于胰岛素泵.
- [1]都健,潘晓黎.胰岛素泵的临床应用及评价[J].2002,(2).
- [2]Kate McKeage,Karen L. Goa.Insulin GlargineA Review of its Therapeutic Use as a Long-Acting Agent for the Management of Type 1 and 2 Diabetes Mellitus[J].2001,61(11).