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Characteristics of inflammation and atherosclerosis in patients with premature stable coronary heart disease combined with impaired glucose regulation
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 2
- DOI:
- 10.3969/j.issn.1006-6187.2009.02.005
- Key Word:
- 动脉粥样硬化;炎症;糖代谢;心血管疾病
Abstract： 目的 探讨合并糖调节受损早发稳定型冠心病(PSCHD)患者(<50岁)循环炎症指标与动脉粥样硬化(AS)特征. 方法 将208例PSCHD患者分为糖调节正常(NGR)组和糖调节受损(IGR)组,分析其临床和生化资料. 结果 IGR组的BMI、TG、尿酸(UA)、高敏C反应蛋白(hsC-RP)、WBC计数、颈动脉内膜中层厚度(IMT)值和斑块比例、代谢综合征和高血压患病率、冠状动脉斑块积分以及多支病变比例均高于NGR组;hsC-RP与WBC计数、BMI及TG正相关,与HDL-C负相关;WBC计数与BMI及UA正相关;P均<0-05或<0-01. 结论 合并IGR的PSCHD患者循环炎症指标和AS程度均显著增加.
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