Abstract： Objective To investigate the prevalences of metabolic disorders of glucose and lipids in the first degree relatives (FDP) of type 2 diabetic patients in Qingdao,China. Methods 1392 subjects were recruited,including 528 T2DM-FDR(parent and/or siblings have T2DM) and 864 NC-FDR(parent and siblings did not have DM). All subjects received both standard 75g oral glucose tolerance test and measurements of body weight,height,waist and hip circumference,percentage of body fat,blood pressure,blood lipid,and plasma uric acid. Results (1) The prevalence of diabetes was higher in DM-FDR than in NC-FDR (24.24% vs 17.01%,P<0.001). (2)Among 128 cases with newly-diagnosed diabetes in DM-FDR group,the prevalences of isolated FPG(≥7.0mmol/L),isolated postprandial hyperglycemia,and combined hyperglycemia were 6.25%,30.47% and 63.28%,respectively. (3) The prevalences of metabolic disorders (including the increased levels of body fat,WHR,blood pressure,triglyceride,low density lipoprotein cholesterol,uric acid) were higher in DM-FDR than in NC-FDR(all P<0.01). (4) Prevalences of one metabolic disorder (any one of diabetes,hypertension,obesity,dyslipidemia),two disorders or metabolic syndrome were significantly higher in DM-FDR than in NC-FDR. Conclusions The prevalences of glucose and lipids disorder are higher in the first degree relatives of diabetes than in general population,which needs to be monitored carefully